Concurrent Multiscale Modeling of Embedded Nanomechanics

Multiscale modeling of the nanomechanics of microtubule protofilaments.

Large-size biomolecular systems that spontaneously assemble, disassemble, and self-repair by controlled inputs play fundamental roles in biology. Microtubules (MTs), which play important roles in cell adhesion and cell division, are a prime example. MTs serve as ″tracks″ for molecular motors, and their biomechanical functions depend on dynamic instability-a stochastic switching between periods ...

A Semi-Concurrent Multiscale Approach for Modeling Damage in Nanocomposites

The paper presents an effective implementation of a semi-concurrent multiscale method in the commercial finite element software package ABAQUS. The method is applied to the pre-localized damage initiation and propagation in the fully exfoliated clay/epoxy nanocomposite. The obtained results of the proposed method is also compared with the hierarchical multiscale approach. This method can be eas...

Multiscale modeling

Principles of Multiscale Modeling

Multiscale Modeling of Malaria

Parasitic infectious diseases like malaria and certain hereditary hematologic disorders are often associated with major changes in the shape and viscoelastic properties of red blood cells. Such changes can disrupt blood flow and, possibly, brain perfusion, as in the case of cerebral malaria. In recent work on stochastic multiscale models—in conjunction with large-scale parallel computing—we wer...